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Therapeutic for hearing loss
Abstract
USC researchers have developed a novel bisphosphonate conjugate of DHF (Ris-DHF). Ris-DHF increases neurite outgrowth in vitro, maintains this ability after binding to hydroxyapatite, and regenerates synapses in kainic acid-damaged cochlear organ of Corti explants dissected in vitro with attached SGNs. The results...
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