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A Method for Quantifying Similarity Between Population Spiking Activities

Variance-weighted neural similarity analytics delivering noise-corrected, reproducible population spike comparisons. Abstract As neural recording systems have expanded in channel density and data complexity, reliably comparing population-level spike activity across trials, sessions, and subjects has remained a significant challenge. Traditional...

2024-126: High-Yield Hydrogen from Ethanol via Acetate Pathways

Background The use of liquid organic hydrogen carriers (LOHCs) for hydrogen storage and transport offers higher volumetric hydrogen densities than compressed gas and utilizes existing liquid fuel infrastructure. Previous attempts of ethanol dehydrogenation give only one equivalent of H2 and form undesirable side reactions. Technology Description This...

Published: 2/24/2026 Inventor(s): Travis Williams, Shayna Kohl, Andrew Rander, Long Zhang
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2025-090 - Advanced CAR T-cell Phenotyping 36-Color Flow Cytometry Panel

Spectral Flow Cytometry High-Parameter Flow Cytometry Multiplex Immunophenotyping Single-Cell Analysis Dimensionality Reduction Data-Driven Cell Profiling Abstract Chimeric Antigen Receptor (CAR) T cell therapy represents a transformative approach in oncology, offering curative potential for patients with relapsed or refractory malignancies....

Published: 2/24/2026 Inventor(s): Mohamed Abou-el-Enein, Christian Flugel, Amaia Cadinanos-Garai
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Category(s): Life Sciences

2025-177 - Dimensionality Reduction for Enhanced Autofluorescence Microscopy (DREAM)

Digital pathology Medical imaging Diagnostic software Life sciences tools Computational imaging Abstract USC researchers have developed a software-based imaging technology that improves visualization of hyperspectral autofluorescence data from unstained tissue samples. The technology converts complex spectral datasets into a compact, information-rich...

Published: 2/24/2026 Inventor(s): Francesco Cutrale, Scott Fraser, Mason Hong, Eun Koo
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2025-190 - A portable image guided ultrasound stimulator

​​​​​Image-guided ultrasound Wearable stimulator Closed-loop targeting Noninvasive pacing Abstract USC researchers have developed a portable, wearable system intended to support noninvasive cardiac rhythm management using an ultrasound-based approach. The technology is designed to deliver controlled cardiac stimulation without implanted leads...

Orally bioavailable pharmaceutical salts of flavenoids

Revolutionizing Post-Alcohol Recovery & Liver Protection with Next-Generation DHM Formulations Enhanced bioavailability through stable salt and co-crystal formulations The Problem DHM has poor solubility and limited absorption, reducing its effectiveness in supporting liver health and alleviating hangover symptoms. The Solution Patented...

Published: 2/13/2026 Inventor(s): Hovhannes Gukasyan, Daryl Davies, Isis Janilkarn-Urena, Paul Seidler
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Category(s): Life Sciences

2024-170 - Deterministic Benchmarking: fast and scalable calibration of qubit logic gates to minimize downtime

Background To enable fault-tolerant quantum computing and reliable quantum simulations for drug development and materials science, quantum hardware must move beyond "noisy" prototypes to commercial-grade stability. Current benchmarking standards often miss systematic coherent errors that accumulate quadratically, creating a hidden bottleneck...

A programmable ultrasound-induced wireless implantable stimulator for personalized chronic pain management

Wireless Ultrasound-Powered Implant for Personalized Chronic Pain Management Abstract USC researchers have developed a flexible, ultrasound-induced wireless implantable stimulator for personalized chronic pain management. The miniaturized device wirelessly harvests ultrasound energy to deliver programmable electrical stimulation for spinal cord...

Published: 1/17/2026 Inventor(s): Qifa Zhou, Chen Gong, Yushun Zeng
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2024-107- Smart Materials and Sensing using Heteroatom-Tuned DASA Photoswitches

Background Donor–acceptor Stenhouse adducts (DASAs) have become valuable photoresponsive materials due to their modular donor, acceptor, and triene components that tune a variety of properties. This attribute is critical for integrating photoswitches into complex devices and biological environments for applications in targeted drug delivery...

2016-094 - Detecting and Correcting Radiation Effects in Electronics

Market Opportunity All electronic devices are susceptible to computational errors due to radiation effects. As electronics get smaller, they are more vulnerable to computational errors due to radiation effects. In mission-critical environments such as military, finance and healthcare, these computational errors are not tolerable. The best solution...

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