Search Results - nan+lee

Reprogramming cancer-associated fibroblasts to normal fibroblasts and M2 to M1 macrophages in tumor microenvironments: A pathway for producing global cancer vaccines

Highlight Reprograms cancer-associated fibroblasts to dismantle tumor barriers and improve immune-cell access to solid tumors. Innovation Cancer-associated fibroblasts (CAFs) create a physical and immunosuppressive barrier that limits the effectiveness of CAR-T and other immunotherapies in solid tumors. This technology uses transcription factor-based...