Description:
- Chemical synthesis
- Genetic and single cell/molecule analysis
- Drug screening
Abstract
USC researchers have developed reusable, in-plane polymer microfluidic interconnects or seamless world-to-chip interfaces. This method uses standard non-coring syringe needles inserted through pre-defined polydimethylsiloxane (PDMS) septa integrated at microchannel inlets/outlets. This design ensures easy batch fabrication, and the septa withstand multiple needle insertions without leaks. These adaptable interconnects promise straightforward integration into various microfluidic systems.
Benefit
- Seamlessly integrates polymer microfluidic interconnects into existing systems
- Pull-out force outperforms comparable interconnects
- Is user-friendly, cost-effective, reliable, versatile, and reusable
Market Application
Microfluidics have facilitated novel diagnostic tools for genetic analysis, drug screening, and single cell/molecule study. Still, current microfluidic interconnects face challenges with inefficient packaging, which hinders their commercial potential. Existing custom interconnects, often out-of-plane, impede optical access and microscope compatibility, while adhesive-based connections prove suboptimal. Addressing these issues presents a pivotal market opportunity for innovative and efficient interconnect solutions.
Publications
Integrated and reusable in-plane microfluidic interconnects, Lo and Meng, 2008.
Stage of Development
- Experimentally validated
- Available for licensing