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2023-086 - Stretchable Microneedle Electrode Arrays for Reliable Intramuscular Electromyography Sensing

Scale bars, 5 mm (top left), 1 mm (top right and middle left), and 3 mm (bottom left and right). Background The field of biomedical sensing has long faced challenges in achieving reliable monitoring of muscle activity within dynamic tissue environments. Conventional microelectrode arrays and surface electrodes often struggle with mechanical instability,...

2026-004: A Method for Quantifying Similarity Between Population Spiking Activities

Variance-weighted neural similarity analytics delivering noise-corrected, reproducible population spike comparisons. Abstract As neural recording systems have expanded in channel density and data complexity, reliably comparing population-level spike activity across trials, sessions, and subjects has remained a significant challenge. Traditional...

2025-090 - Advanced CAR T-cell Phenotyping 36-Color Flow Cytometry Panel

Spectral Flow Cytometry High-Parameter Flow Cytometry Multiplex Immunophenotyping Single-Cell Analysis Dimensionality Reduction Data-Driven Cell Profiling Abstract Chimeric Antigen Receptor (CAR) T cell therapy represents a transformative approach in oncology, offering curative potential for patients with relapsed or refractory malignancies....

Published: 3/26/2026 Inventor(s): Mohamed Abou-el-Enein, Christian Flugel, Amaia Cadinanos-Garai
Category(s): Life Sciences

2025-177 - Dimensionality Reduction for Enhanced Autofluorescence Microscopy (DREAM)

Digital pathology Medical imaging Diagnostic software Life sciences tools Computational imaging Abstract USC researchers have developed a software-based imaging technology that improves visualization of hyperspectral autofluorescence data from unstained tissue samples. The technology converts complex spectral datasets into a compact, information-rich...

2025-190 - A portable image guided ultrasound stimulator

​​​​​Image-guided ultrasound Wearable stimulator Closed-loop targeting Noninvasive pacing Abstract USC researchers have developed a portable, wearable system intended to support noninvasive cardiac rhythm management using an ultrasound-based approach. The technology is designed to deliver controlled cardiac stimulation without implanted leads...

Orally bioavailable pharmaceutical salts of flavenoids

Revolutionizing Post-Alcohol Recovery & Liver Protection with Next-Generation DHM Formulations Enhanced bioavailability through stable salt and co-crystal formulations The Problem DHM has poor solubility and limited absorption, reducing its effectiveness in supporting liver health and alleviating hangover symptoms. The Solution Patented...

Published: 2/13/2026 Inventor(s): Hovhannes Gukasyan, Daryl Davies, Isis Janilkarn-Urena, Paul Seidler
Category(s): Life Sciences

A programmable ultrasound-induced wireless implantable stimulator for personalized chronic pain management

Wireless Ultrasound-Powered Implant for Personalized Chronic Pain Management Abstract USC researchers have developed a flexible, ultrasound-induced wireless implantable stimulator for personalized chronic pain management. The miniaturized device wirelessly harvests ultrasound energy to deliver programmable electrical stimulation for spinal cord...

2022-121 - Bio-PICS: Bio-Photonics Point of Care Sensors

COVID-19 detection Viral detection Cancer marker detection Abstract USC inventors propose a novel selectively-sensing bio-photonics microfluidic optical ring resonator-based integrated chip architecture with an on-chip spectrometer consisting of coupled ring resonator filters and integrated photodetector arrays for detection of COVID-19. The design...

Cora mobile app

Market Opportunity Patients with implantable devices like pacemakers or defibrillators need ongoing monitoring for optimal device performance and early detection of issues. Currently, patients lack direct access to their device data and rely on clinician reviews. Existing solutions often have fragmented, confusing interfaces and limited educational...

2021-166 - AI Driven Modular Method for Structure-Based Screening of Virtual Libraries

Market Opportunity Structure-based virtual ligand screening is emerging as a key paradigm for early drug discovery owing to the availability of high-resolution target structures and ultra-large libraries of virtual compounds. However, to keep pace with the explosive growth of virtual chemical libraries, new approaches to compound screening are needed. USC...

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