Search Results - yeong+hye+park

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2023-021 - Novel chemical compounds regulating Piezo1 activity

Novel small-molecule Piezo1 agonists with high selectivity, strong metabolic stability, and minimal CYP450 interactions Enhances cerebrospinal fluid and lymphatic drainage through activation of Akt and eNOS signaling pathways Demonstrated reduction of ventricular fluid accumulation in hydrocephalus animal models, supporting therapeutic potential for...