Search Results - leonardo+morsut

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2023-085 - Methods for controlling spatial differentiation for Tissue Engineering

Organoids and tissue engineering for applications in regenerative medicine, drug testing, transplantaion, and design of protein rich food sources. Abstract USC researchers have developed a system for precise spatial control of gene expression within multicellular constructs. The technology utilizes engineered cells and matrix materials to present...

2025-028 - Method for controlling patterning of kidney-like constructs in vitro from stem cells

kidney patterning organoid patterning synthetic organizers Abstract USC researchers have bioengineered WNT secreting cells that act as synthetic organizers, imitating the collecting duct-localized production of WNT ligands. Organizer-coupled nephrons polarized and directed their distal tubules towards the WNT-source, indicating that both patterning...