Search Results - megan+mccain

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2023-085 - Methods for controlling spatial differentiation for Tissue Engineering

Abstract USC researchers have developed a system for precise spatial control of gene expression within multicellular constructs. The technology utilizes engineered cells and matrix materials to present signaling ligands and activate synthetic Notch (synNotch) receptors through customizable material-to-cell signaling pathways, enabling controlled cell...

2017-237 - Fluidic Device for Long-Term Explant Culture and Imaging

Research tool for drug discovery in regenerative medicine Abstract USC and CHLA researchers have designed and fabricated a fluidic device to maintain flow into the culture, which overcomes the problem of lack of blood flow into and around the organ and ensures the structure of the organs is maintained. Using this fluidic device researchers were able...