Search Results - scott+fraser

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2025-177 - Dimensionality Reduction for Enhanced Autofluorescence Microscopy (DREAM)

Digital pathology Medical imaging Diagnostic software Life sciences tools Computational imaging Abstract USC researchers have developed a software-based imaging technology that improves visualization of hyperspectral autofluorescence data from unstained tissue samples. The technology converts complex spectral datasets into a compact, information-rich...

Published: 2/24/2026 Inventor(s): Francesco Cutrale, Scott Fraser, Mason Hong, Eun Koo
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2015-115 - CRISPR-Cas9 Gene Editing Tool

Gene editing toolbox for integrating larger genome sequences Abstract USC inventors have developed recombinant fusion proteins that actively recruit linear DNA inserts in closer proximity to the genomic cleavage site, thereby allowing increasing integration efficiency, particularly of large DNA fragments, into the genome. Such improvements to genomic...

2017-111 - Optimized Volumetric Imaging with Selective Volume Illumination & Light Field Detection

Live 3D imaging Volumetric imaging over time (4D) Multi-label imaging (5D) Abstract USC inventors can generate accurate volumetric images by employing Selective Volume Illumination (SVI), where only the relevant part of the 3D sample is illuminated, offering better contrast and signal-to-noise for the light field calculations. SVI is compatible...

Published: 11/13/2025 Inventor(s): Thai Truong, Scott Fraser, Sara Madaan, Daniel Holland
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2022-127 - Polarization-Maintaining Fiber for Surface-Enhanced Raman Spectroscopy

Chemical and biological sensing Pharmaceutical analysis Surface and material science Abstract USC researchers have developed a method for fiber-based SERS that utilizes polarization-controlled plasmonic excitation. By employing two controllable, perpendicular directions of polarization along a fiber, the technique minimizes Raman signals generated...

Published: 11/6/2025 Inventor(s): Scott Fraser, Chieh-feng Chang
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