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Background
Functional ultrasound imaging is a promising neuroimaging technology with potential to unlock next-generation brain-computer interfaces (BCI). However, ultrasound imaging through the skull is limited by the impedance mismatch between bone and brain tissue, causing reflection, scattering, and signal loss, resulting in poor transmission and...
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Uses steady-state visually evoked potentials (SSVEPs) as endogenous reference signals for cross-session EEG calibration.
Creates a subject-specific linear mapping that aligns raw EEG recordings to a common neural baseline.
Reduces the impact of session dependent recording differences to support consistent longitudinal EEG analysis.
Abstract
This...
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Scale bars, 5 mm (top left), 1 mm (top right and middle left), and 3 mm (bottom left and right).
Background
The field of biomedical sensing has long faced challenges in achieving reliable monitoring of muscle activity within dynamic tissue environments. Conventional microelectrode arrays and surface electrodes often struggle with mechanical instability,...
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Image-guided ultrasound
Wearable stimulator
Closed-loop targeting
Noninvasive pacing
Abstract
USC researchers have developed a portable, wearable system intended to support noninvasive cardiac rhythm management using an ultrasound-based approach. The technology is designed to deliver controlled cardiac stimulation without implanted leads...
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Wireless Ultrasound-Powered Implant for Personalized Chronic Pain Management
Abstract
USC researchers have developed a flexible, ultrasound-induced wireless implantable stimulator for personalized chronic pain management. The miniaturized device wirelessly harvests ultrasound energy to deliver programmable electrical stimulation for spinal cord...
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Electrical recording and stimulation
Management of diseases such as epilepsy
Electrophysiological research
Abstract
USC researchers have developed a thin film electrode array that can be implanted using endovascular methods for minimally-invasive, high-resolution electrical recording and stimulation of the nervous system and other electrogenic...
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EMG technology
Supplement to HRV technology
Spinal injuries and paralysis, cardiac cases, and muscle injuries
Abstract
USC researchers have discovered an improved method to analyze the sinusoidal signals induced by the central pattern generator (CPG) in the spine using surface electromyographic (sEMG) activity. The proposed technique identifies...
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Easy method to make antibody-drug conjugates that target specific sites
Can be used to kill HER2-expressing breast cancer cells
May be used to deliver drugs for other purposes
Abstract
Researchers at USC developed an innovative class of site-specific ADCs that can be generated in just a single step by coupling proprietary bifunctional antibody...
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Vision research and diagnosis
Intravascular imaging for cardiological stents
Esophagus imaging for cancer surveillance
Abstract
USC researchers have developed a novel full-field OCT approach that increases imaging speed while reducing overall hardware cost by a factor of 5-10. The technique exploits recent developments in additive manufacturing...
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Antiviral drugs
Effective against Covid-19
Abstract
USC researchers engineered nanoscale barriers capable of lipid interactions with viruses, thus interfering with membrane fusion, and membrane remodeling preventing viral entry and replication. The HPBCD-based platform can safely interact with existing mucocutaneous protective barriers capable of...
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