Search Results - clay+wang

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2021-005 - Efficient Platform for the Biosynthesis of Natural Products

Biosynthesis of natural products Elucidating cryptic biosynthesis pathways Abstract USC researchers set out to devise a biosynthetic gene clusters (BGC) refactoring strategy and heterologous expression platform in A. nidulans based on the afo regulon. Taking advantage of the transcriptional regulatory elements of afo, the afo genes were replaced...

Published: 12/15/2025 Inventor(s): Yi-Ming Chiang, Clay Wang
Keywords(s):  
Category(s): Life Sciences > Biomaterials & Bioprinting, Life Sciences

11-692 - Polypeptide Nanoparticles for Controlled Release of Ocular Biopharmaceuticals

Novel protein-based targeted drug delivery strategy Potential application to treat several ocular disorders Uses biocompatible, biodegradable and less immunogenic ELP-1 polymers Abstract USC scientists genetically engineered elastin-like polypeptides (ELP), which assemble multivalent nanoparticles at physiological temperature. The innovation was...

Published: 12/12/2025 Inventor(s): John MacKay, Wan Wang
Keywords(s):  
Category(s): Life Sciences > Therapeutics & Drug Development

2022-191 - Conversion of Waste Plastics to High-Value Metabolites

Abstract USC researchers have developed an approach to convert polyethylenes into valuable compounds. This method involves aerobic, catalytic digestion of polyethylenes obtained from post-consumer and oceanic waste streams. The resulting carboxylic diacids serve as a carbon source for the fungus Aspergillus nidulans. Through genetic engineering, strains...

Keywords(s):  
Category(s): Physical Sciences & Engineering > Energy & Sustainability