Search Results - julio+camarero+palao

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2020-143 - Engineered Cyclotides with Potent Broad Antimicrobial Activity

Antibacterial therapeutic Abstract USC researchers engineered novel cyclotide with effective broad-spectrum antibacterial activity against several ESKAPE bacterial strains and clinical isolates. Cyclotides are micro-proteins (˜30 residues long) that have shown remarkable stability, are easily synthesized and have shown good oral bioavailability....

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Category(s): Life Sciences, Life Sciences > Therapeutics & Drug Development

2021-234 - Potent Anti-Cancer Cyclotides

Colorectal cancer treatment Abstract Our R&D team developed a cell-permeable Hdm2/HdmX E3 ligase inhibitor that shows in vitro activity in many cancer cell-lines (prostate carcinoma, osteosarcoma, lung carcinoma, colon carcinoma and ovarian carcinoma, among others) with p53 wt, mutated or null. This compound has shown activity in a colorectal...

Published: 2/3/2026 Inventor(s): Julio Camarero Palao, Dipankar Chaudhuri
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Category(s): Life Sciences, Life Sciences > Therapeutics & Drug Development