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2020-143 - Engineered Cyclotides with Potent Broad Antimicrobial Activity

Antibacterial therapeutic Abstract USC researchers engineered novel cyclotide with effective broad-spectrum antibacterial activity against several ESKAPE bacterial strains and clinical isolates. Cyclotides are micro-proteins (˜30 residues long) that have shown remarkable stability, are easily synthesized and have shown good oral bioavailability....