|
Prognostic biomarkers for brain tumors and immunotherapies for glioblastoma multiforme
RNA based biotherapeutics
Abstract
USC researchers have discovered long non-coding RNAs (lncRNAs) that were aberrantly expressed specifically in GBM brains relative to normal brains. These lncRNAs had prognostic significance and could serve as prognostic...
|
|
Bioinformatics
Personal genomics
Abstract
USC researchers have designed the first tool that bridges genomic data mining and prior cancer search knowledge. This statistical model leverages personal genomic information with a large biological database to facilitate cancer diagnostics and personalize cancer treatment.
Benefit
User-friendly tool
Facilitate...
|
|
Bioinformatics
Personal genomics
Abstract
USC researchers have developed an integrative tool named Phenolyzer, a phenotype-based gene analyzer. Phenolyzer takes a discrete list of phenotype terms as input and generates a list of candidate genes weighted by the chance of being associated with the phenotype, even in the absence of any genotype data....
|
|
Novel protein-based targeted drug delivery strategy
Potential application to treat several ocular disorders
Uses biocompatible, biodegradable and less immunogenic ELP-1 polymers
Abstract
USC scientists genetically engineered elastin-like polypeptides (ELP), which assemble multivalent nanoparticles at physiological temperature. The innovation was...
|