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2017-147 - Elastin-like Polypeptide Fusion Proteins Establish Novel Drug Carrier Strategy

Treatment for organ rejection and autoimmune diseases Drug carrier Abstract USC researchers have developed a novel strategy to carry CsA by binding it to its cognate receptor, cyclophilin. Significantly improved pharmacokinetic (PK) profile and therefore reduced systemic side effect were achieved by fusing cyclophilin with different types of elastin-like...

Published: 12/13/2025 Inventor(s): John MacKay, Sarah Hamm-Alvarez, Mihir Shah, Hao Guo
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