Search Results - sarah+hamm-alvarez

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2017-147 - Elastin-like Polypeptide Fusion Proteins Establish Novel Drug Carrier Strategy

Treatment for organ rejection and autoimmune diseases Drug carrier Abstract USC researchers have developed a novel strategy to carry CsA by binding it to its cognate receptor, cyclophilin. Significantly improved pharmacokinetic (PK) profile and therefore reduced systemic side effect were achieved by fusing cyclophilin with different types of elastin-like...

Published: 12/13/2025 Inventor(s): John MacKay, Sarah Hamm-Alvarez, Mihir Shah, Hao Guo
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10-235 - Rapamycin to Treat Sjögren's Syndrome

New use for an FDA approved therapeutic with established safety profile in patients with Sjögren's syndrome Abstract USC researchers have developed a customizable platform able USC researchers demonstrated that rapamycin shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjögren’s syndrome. The...

Published: 12/12/2025 Inventor(s): Sarah Hamm-Alvarez
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