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2024-143 - Novel N-(chroman-3-yl) benzamide analogs as potent antimicrobial agents, and immune activators

Abstract USC scientists have developed novel N-(chroman-3-yl) benzamide compounds, which have shown potent antimicrobial activity against antibiotic-resistant Staphylococcus aureus (SA) and enhanced immune cell killing. In vitro tests revealed a four-fold reduction in the concentration needed to inhibit the growth of the bacterium. When these compounds...

Published: 11/13/2025 Inventor(s): Annie Wong-Beringer, Syed Ahmed, Paul Beringer, Vy Nguyen, Riley Grosso
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